Summary: Many US states published crisis standards of care (CSC) guidelines for allocating scarce critical care resources during the COVID-19 pandemic.However, the performance of these guidelines in maximizing their population benefit has not been well tested.In 2,272 adults with COVID-19 requiring mechanical ventilation drawn from the Study of the
BACKGROUND:Fibrosis, the excessive deposition of scar tissue by fibroblasts, is one of the largest groups of diseases for which there is no therapy.Fibroblasts from lesional areas of scleroderma patients possess elevated abilities to contract matrix and produce alpha-smooth muscle actin (alpha-SMA), type I collagen and CCN2 (connective tissue growt
In this study, we hypothesized that the limited geographical distribution of Pseudopungtungia tenuicorpa in South Korea is closely related to the local abundance of their preferred spawning habitats.Eggs of P.tenuicorpa were most frequently observed in cracks smaller than 5 cm, followed by the nests of other fish, such as Coreoperca herzi.Although
Black morel, a widely prized culinary delicacy, was once an uncultivable soil-saprotrophic ascomycete mushroom that can now be cultivated routinely in farmland soils.It acquires carbon nutrients from an aboveground nutritional supplementation, while it remains unknown how the morel mycelium together with associated microbiota in the substratum meta
Although issues related to the management of invasive alien species are receiving increasing attention, little is known about which factors affect the likelihood of success of management measures.We applied two data mining techniques, classification trees and boosted trees, to identify factors that relate to the success of management campaigns aime